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Maquart 1988 J Clin Invest showed that GHK-Cu at nanomolar concentration stimulates type I collagen synthesis by fibroblasts by 60-200 %, of glycosaminoglycans (hyaluronic acid, heparan sulphate) and proteoglycans

Although the predominant species found in the plasma is NAP (Calvo et al ., 1987), that is extensively bound to plasma proteins mainly albumin (Bischer et al ., 1995), it is excreted almost exclusively in the form of metabolites in the urine (Anderson and Hansen, 1992)

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